Mutated Genes, Pathways, Processes and protein Domains in tumours web application.

Mutated Genes

Data on the mutations were retrieved from 3 databases, 4 whole-genome resequencing studies and finally, resequencing screens focusing on subsets of genes of interest or preselected candidate cancer genes. All the genes with at least one non-synonymous mutation in their coding sequence or at a splice site were taken into account, and matched to Ensembl IDs. The mutated genes were mapped to the tumour type in which they have been seen to be mutated, trying to follow the ICD10 topographic neoplasm classification, when possible